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Fatigatio e.V.

Autoantibodies to beta-adrenergic and muscarinic cholinergic receptors in Myalgic Encephalomyelitis (ME) patients (

Datum: 07.08.2020 Kategorie: 07 Fatigatio e.V. Autor: MKK (kanter)

A validation study in plasma and cerebrospinal fluid from two Swedish cohorts


  • Myalgic Encephalomyelitis (ME) is a devastating disorder (with millions of patients worldwide) with unclear aetiology and no clear diagnostic biomarker available.
  • This study support the existance of a general pattern of increased antibody levels to adrenergic and muscarinic receptors within the ME patient group.
  • No evidence for intrathecal antibody production was found in cerebrospinal fluid. The role of increased autoantibodies in the pathogenesis of ME is still uncertain and further research is needed to evaluate their clinical significance.

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